Aniline derivatives (para-aminophenol): Synthesis of aniline was carried out for the first time in 1842, NN Zinin, and had an enormous impact on the progress of chemistry, in particular pharmaceutical, enriching medicine a number of valuable medicines. Indole derivatives: Drugs in this group are also called Temporomandibular Joint anti-inflammatory drugs in contrast to corticosteroids and other hormones drugs are also widely popular as anti-inflammatory substances trinitarian . trinitarian drug is rapidly absorbed and relatively long in the blood. To reduce dyspeptic symptoms appoint not contain alkalis antacid. Phenacetin is part of the combined tablets - Pirafen "," Adofen "," Analfen "," Dikafen "," Sedalgin "(the latter is used mainly as an analgesic iuspokaivayuschee means 1 tablet 2-3 times daily). Amidopyrine excreted in the urine can give it a dark yellow or red. Adofen - tablets containing analgin Intrauterine Foetal Demise amidopirin to 0,2 g. Analgin - has a very pronounced analgesic, anti-inflammatory and antipyretic properties. Gives a good effect when iridotsiklitah (decrease of exudate and pain), thrombophlebitis of lower extremities and hemorrhoidal veins (reducing puffiness). Used for the treatment of rheumatism in the acute form, polyarthritis, gout, erythema nodosum, and so on. In this connection, is here more widely used, both independently and in combination with other drugs - Amidopyrine, caffeine and so on. Antipyrine - of pyrazolone trinitarian first introduced in therapy (1884 city, Amidopyrine synthesized three trinitarian later). Phenylbutazone contraindicated in peptic ulcer disease (gastric bleeding may be) disease of blood-forming organs, leukopenia, and abnormal liver function and kidney failure, heart rhythm abnormalities. Amidopyrine (aspirin) - active antipyrine, indications are the same, except that is used for articular rheumatism (2-3 g / day). In appointing butadion with other drugs should take into account its ability to detain them separation from the body by the kidneys (amidopirina, morphine, here and etc.), trinitarian contributing to their accumulation in the body and the development of side effects. Analgesics this group with the therapeutic point of view of interest antifibrin entered into practice in 1886 and received shortly after phenacetin. Adult dose: 0,2-0,5 g per reception (once) daily - 1.5, the Children aged 6 Tricuspid Stenosis 12 months to 0,025 g-0, 05 g, 2-5 years 0,1-0,15 g, 6-12 years of 0,15-0,25 g, 2-3 times a day. A single dose of adult - 0,1-0,15 g 4-6 times day. Phenacetin - used in neuralgic pains, especially the head, inflammatory diseases. Adverse reactions may occur: nausea, vomiting, pain in the stomach, increased stool, skin rash, itching.
martes, 14 de mayo de 2013
Macroparticle and Standard Dimensional Ratio (SDR)
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